[BioC] gdata affects LumiBatch::combine method
Mark Cowley
m.cowley at garvan.org.au
Tue Oct 9 06:40:30 CEST 2012
Dear list,
i'm trying to combine two LumiBatch objects, using the S4 combine("LumiBatch","LumiBatch") method, defined originally in BiocGenerics, and enhanced within lumi.
In a fresh session, with just lumi loaded, everything works fine, i.e. I get a LumiBatch object.
As soon as I load gdata, this breaks the combine method, instead returning a data.frame with very odd dimensions. This is true if I load gdata before, or after lumi. Note that showMethods("lumi") doesn't change after loading gdata. Any ideas?
cheers,
Mark
### lumi, then gdata
> suppressPackageStartupMessages(library(lumi))
Warning messages:
1: found methods to import for function ‘eapply’ but not the generic itself
2: replacing previous import ‘image’ when loading ‘graphics’
> load("Rmisc/n525.RDa")
> load("Rmisc/s295.RDa")
> showMethods("combine")
Function: combine (package BiocGenerics)
x="AnnotatedDataFrame", y="AnnotatedDataFrame"
x="ANY", y="missing"
x="AssayData", y="AssayData"
x="data.frame", y="data.frame"
x="eSet", y="eSet"
x="ExpressionSet", y="LumiBatch"
x="LumiBatch", y="ExpressionSet"
x="LumiBatch", y="LumiBatch"
x="matrix", y="matrix"
x="MethyLumiM", y="MethyLumiM"
x="MethyLumiQC", y="MethyLumiQC"
x="MethyLumiSet", y="MethyLumiSet"
x="MIAME", y="MIAME"
> a <- combine(n525, s295)
> class(a)
[1] "LumiBatch"
attr(,"package")
[1] "lumi"
## the expected output
> suppressPackageStartupMessages(library(gdata))
> showMethods("combine")
Function: combine (package BiocGenerics)
x="AnnotatedDataFrame", y="AnnotatedDataFrame"
x="ANY", y="missing"
x="AssayData", y="AssayData"
x="data.frame", y="data.frame"
x="environment", y="environment"
(inherited from: x="AssayData", y="AssayData")
x="eSet", y="eSet"
x="ExpressionSet", y="LumiBatch"
x="LumiBatch", y="ExpressionSet"
x="LumiBatch", y="LumiBatch"
x="matrix", y="matrix"
x="MethyLumiM", y="MethyLumiM"
x="MethyLumiQC", y="MethyLumiQC"
x="MethyLumiSet", y="MethyLumiSet"
x="MIAME", y="MIAME"
> a <- combine(n525, s295)
> class(a)
[1] "data.frame"
>
#### gdata then lumi
> suppressPackageStartupMessages(library(gdata))
> suppressPackageStartupMessages(library(lumi))
Warning messages:
1: found methods to import for function ‘eapply’ but not the generic itself
2: replacing previous import ‘image’ when loading ‘graphics’
> load("Rmisc/n525.RDa")
> load("Rmisc/s295.RDa")
> showMethods("combine")
Function: combine (package BiocGenerics)
x="AnnotatedDataFrame", y="AnnotatedDataFrame"
x="ANY", y="missing"
x="AssayData", y="AssayData"
x="data.frame", y="data.frame"
x="eSet", y="eSet"
x="ExpressionSet", y="LumiBatch"
x="LumiBatch", y="ExpressionSet"
x="LumiBatch", y="LumiBatch"
x="matrix", y="matrix"
x="MethyLumiM", y="MethyLumiM"
x="MethyLumiQC", y="MethyLumiQC"
x="MethyLumiSet", y="MethyLumiSet"
x="MIAME", y="MIAME"
> a <- combine(n525, s295)
> class(a)
[1] "LumiBatch"
attr(,"package")
[1] "lumi"
> sessionInfo()
R version 2.15.1 (2012-06-22)
Platform: i386-apple-darwin9.8.0/i386 (32-bit)
locale:
[1] en_AU.UTF-8/en_AU.UTF-8/en_AU.UTF-8/C/en_AU.UTF-8/en_AU.UTF-8
attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] lumi_2.10.0 nleqslv_1.9.4 Biobase_2.18.0 BiocGenerics_0.4.0
[5] gdata_2.12.0
loaded via a namespace (and not attached):
[1] affy_1.36.0 affyio_1.26.0 annotate_1.36.0
[4] AnnotationDbi_1.20.0 BiocInstaller_1.8.1 colorspace_1.1-1
[7] DBI_0.2-5 grid_2.15.1 gtools_2.7.0
[10] IRanges_1.16.2 KernSmooth_2.23-8 lattice_0.20-10
[13] MASS_7.3-22 Matrix_1.0-9 methylumi_2.4.0
[16] mgcv_1.7-21 nlme_3.1-104 parallel_2.15.1
[19] preprocessCore_1.20.0 RSQLite_0.11.2 stats4_2.15.1
[22] XML_3.95-0.1 xtable_1.7-0 zlibbioc_1.4.0
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