[BioC] DNAcopy for CNV in SNP Affy 6.0

Ekta Jain Ekta_Jain at jubilantbiosys.com
Tue Apr 3 10:38:29 CEST 2012


Dear BioC Help,
I am having issues with the CGHcall package when using in R. I first employ DNAcopy package to smooth and segment my data (CNA.object) and get an error while performing post normalize processing using the CGHcall package.

> smoothed.CNA.object <- smooth.CNA(CNA.object)
> segment.smoothed.CNA.object <- segment(smoothed.CNA.object, verbose=1) 
Analyzing: ABC1 
Analyzing: BEN
> postseg.cghdata <- postsegnormalize(segment.smoothed.CNA.object)
Error in function (classes, fdef, mtable)  : 
  unable to find an inherited method for function "segmented", for signature "DNAcopy"

Is there any structural difference between CNA object and CGH object type? Please do let me know where i could possibly be going wrong.

Thank you,
Ekta

> sessionInfo()
R version 2.14.1 (2011-12-22)
Platform: i386-pc-mingw32/i386 (32-bit)

locale:
[1] LC_COLLATE=English_India.1252  LC_CTYPE=English_India.1252   
[3] LC_MONETARY=English_India.1252 LC_NUMERIC=C                  
[5] LC_TIME=English_India.1252    

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] CGHcall_2.14.0      CGHbase_1.12.0      marray_1.34.0      
[4] limma_3.10.3        Biobase_2.14.0      impute_1.28.0      
[7] DNAcopy_1.28.0      BiocInstaller_1.2.1

loaded via a namespace (and not attached):
[1] tools_2.14.1
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