[BioC] Detecting Up-Regulated Genes

Sean Davis sdavis2 at mail.nih.gov
Thu Sep 8 18:10:52 CEST 2011


On Thu, Sep 8, 2011 at 12:06 PM, ANIRBAN BHAR <aec.ani at gmail.com> wrote:
> Hi all,
>
> I have an Time-course dataset where each gene has expression values over
> some time-points and each time-point has some replicates. Now how can we
> detect up-regulated genes between two time points using some standard
> procedure (may be some statistical test)? I am interested to have an idea
> about the work-flow.

Hi, Anirban.

You might take a look at the limma package as a starting place.  Your
different time points will be different groups.

Sean



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